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Home TrueClone ADRB2 Clone

ADRB2 (NM_000024) Human cDNA Clone

Specifications Citations (4) Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC116997 ADRB2 (untagged)-Human adrenergic, beta-2-, receptor, surface (ADRB2) (10ug), NM_000024.3, 10ug $185 2 weeks
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA317555 ADRB2 Rabbit Polyclonal (C-Terminus) Antibody, 50ug $345 3-7 Days
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OriGene Data
Vector:pCMV6-XL5 Insert Size: 2050 Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: GPCRTransmembraneDruggable Genome
Protein Pathways: Calcium signaling pathwayNeuroactive ligand-receptor interactionEndocytosis
Reference Data
RefSeq: NM_000024.3, NP_000015
RefSeq Size: 2015 RefSeq ORF: 1242
Synonyms : ADRB2R; ADRBR; B2AR; BAR; BETA2AR
LocusID: 154 Cytogenetic: 5q31-q32 Domains: 7tm_1
Summary: This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Jul 2008].


* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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