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Home TrueClone CEL Clone

CEL (BC042510) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC125747 CEL (untagged)-Human carboxyl ester lipase (bile salt-stimulated lipase), mRNA (cDNA clone MGC:35409 IMAGE:5187959), complete cds (10ug), BC042510.1, 10ug $185 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TT200002 MegaTran 1.0 (0.5ml), 165 rxns for 24-well plates, 0.5ml $90 In Stock
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OriGene Data
Vector:pCMV6-XL5 Insert Size: Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Druggable Genome
Protein Pathways: Steroid biosynthesisGlycerolipid metabolismMetabolic pathways
Reference Data
RefSeq: BC042510.1, AAH42510
RefSeq Size: 2316 RefSeq ORF: 2169
Synonyms : LIPA; BAL; BSDL; BSSL; CELL; CEase; FAP; FAPP; MODY8; OTTHUMP00000022450; bile salt-dependent lipase, oncofetal isoform; bile salt-stimulated carboxyl ester lipase; bile salt-stimulated lipase; bile-salt-activated lipase; carboxyl ester hydrolase; carboxy
LocusID: 1056 Cytogenetic: 9q34.3
Summary: The protein encoded by this gene is a glycoprotein secreted from the pancreas into the digestive tract and from the lactating mammary gland into human milk. The physiological role of this protein is in cholesterol and lipid-soluble vitamin ester hydrolysis and absorption. This encoded protein promotes large chylomicron production in the intestine. Also its presence in plasma suggests its interactions with cholesterol and oxidized lipoproteins to modulate the progression of atherosclerosis. In pancreatic tumoral cells, this encoded protein is thought to be sequestrated within the Golgi compartment and is probably not secreted. This gene contains a variable number of tandem repeat (VNTR) polymorphism in the coding region that may influence the function of the encoded protein. [provided by RefSeq, Jul 2008].


* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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