Silencing hsp25/hsp27 Gene Expression Augments Proteasome Activity and Increases CD8+ T-Cell–Mediated Tumor Killing and Memory Responses
Cancer Prevention Research, Jan 2012; 5: 122 - 137.
[HSPB1
]
Activation of Androgen Receptor, Lipogenesis, and Oxidative Stress Converged by SREBP-1 Is Responsible for Regulating Growth and Progression of Prostate Cancer Cells
Mol. Cancer Res., Jan 2012; 10: 133 - 142.
[SREBF1
]
Androgen Deprivation Causes Epithelial–Mesenchymal Transition in the Prostate: Implications for Androgen-Deprivation Therapy
Cancer Res., Jan 2012; 72: 527 - 536.
[AR
]
CB2 Cannabinoid Receptors Promote Neural Progenitor Cell Proliferation via mTORC1 Signaling
J. Biol. Chem., Jan 2012; 287: 1198 - 1209.
[Cnr2
]
ORFs cloned in this vector will be expressed in mammalian cells as fusion proteins with 3 tandem DDK-tags on the C-terminal ends, resulting in 100X higher detection sensitivity than 1XDDK tag
The 3DDK tag will increase the affinity of the fusion protein to anti-DDK tags and facilitate detection. This is especially useful for proteins of low expression level.
If the C-terminal tagging interferes with the protein’s function, you can choose the N-terminal 3DDK-tagging vector, PS100058.