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Home TrueClone PTPRD Clone

PTPRD (NM_130391) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC120547 PTPRD (untagged)-Human protein tyrosine phosphatase, receptor type, D (PTPRD), transcript variant 2 (10ug) NM_130391.1, 10ug $980 7 weeks
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA319072 Rabbit polyclonal anti-PTPRD antibody (NT), 100ug $345 3-7 Days
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OriGene Data
Vector:pCMV6-XL4 Insert Size: 2940 Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: TransmembranePhosphataseDruggable Genome
Reference Data
RefSeq: NM_130391.1, NP_569075
RefSeq Size: 8266 RefSeq ORF: 4518
Synonyms : HPTP; HPTPD; HPTPDELTA; PTPD; RPTPDELTA
LocusID: 5789 Cytogenetic: 9p23 Domains: PTPc, ig, PTPc_motif, IGc2, IG, FN3
Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Jan 2010].

Transcript Variant: This variant (2) has multiple differences in the coding region, compared to variant 1, resulting in an isoform (2) that is shorter than isoform 1. The 5' UTR of this variant is incomplete because no 5' complete transcripts representing this variant exist, and there are alternate splicing choices in the upstream region.

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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