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Home TrueClone PTPN7 Clone

PTPN7 (NM_080588) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC128004 PTPN7 (untagged)-Human protein tyrosine phosphatase, non-receptor type 7 (PTPN7), transcript variant 2 (10ug) NM_080588.1, 10ug $680 4 weeks
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA503662 PTPN7 (HePTP) mouse monoclonal antibody, Clone 3H8, 100ul $325 In Stock
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OriGene Data
Vector:pCMV6-XL5 Insert Size: 2700 Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: PhosphataseDruggable Genome
Protein Pathways: MAPK signaling pathway
Reference Data
RefSeq: NM_080588.1, NP_542155
RefSeq Size: 3265 RefSeq ORF: 1200
Synonyms : BPTP-4; HEPTP; LC-PTP; LPTP; PTPNI
LocusID: 5778 Cytogenetic: 1q32.1
Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2010].

Transcript Variant: This variant (2) lacks an exon from the 5' end and contains an alternate 5' segment which includes an AUG start codon, as compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus, as compared to isoform 1.

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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