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Home TrueClone CHEK2 Clone

CHEK2 (NM_007194) Human Kinase Deficient Mutant

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC323572 CHEK2 (untagged)-Kinase deficient mutant (K249M) of Human CHK2 checkpoint homolog (S. pombe) (CHEK2), transcript variant 1 (10ug) NM_007194.3, 10ug $680 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA500384 CHEK2 (CHK2) mouse monoclonal antibody, clone 2H5, 100ul $325 In Stock
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Click here for the corresponding wild type clone.

OriGene Data
Vector:pCMV6-XL5 Insert Size: 1920 Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          Kinase domain sequence
OTI Annotation: This kinase-deficient mutant clone was generated by created by site-directed mutagenesis from the corresponding wild-type clone. See details in "Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling." Cell. 2008 May p536-548.
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Protein KinaseStem cell - PluripotencyDruggable Genome
Protein Pathways: Cell cyclep53 signaling pathway
Reference Data
RefSeq: NM_007194.3, NP_009125
RefSeq Size: 1862 RefSeq ORF: 1632
Synonyms : CDS1; CHK2; hCds1; HuCds1; LFS2; PP1425; RAD53
LocusID: 11200 Cytogenetic: 22q12.1 Domains: FHA, pkinase, TyrKc, S_TKc
Summary:

Transcript Variant: This variant (1) represents the predominant transcript and encodes isoform a.

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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