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Home TrueClone SKIL Clone

SKIL (NM_005414) Human cDNA Clone

Specifications Citations (1) Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC116749 SKIL (untagged)-Human SKI-like oncogene (SKIL), transcript variant 1 (10ug), NM_005414.2, 10ug $185 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA800162 SKIL (SnoN) mouse monoclonal antibody, Clone 3E2, 100ul $325 In Stock
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OriGene Data
Vector:pCMV6-XL4 Insert Size: 3700 Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Transcription FactorsDruggable Genome
Reference Data
RefSeq: NM_005414.2, NP_005405
RefSeq Size: 7202 RefSeq ORF: 2055
Synonyms : SNO; SnoA; SnoI; SnoN
LocusID: 6498 Cytogenetic: 3q26 Domains: Ski_Sno
Summary: The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].

Transcript Variant: This variant (1) encodes the longest isoform (1, also known as snoN).

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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