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Home TrueClone HDAC1 Clone

HDAC1 (NM_004964) Human cDNA Clone

Specifications Citations (4) Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC117054 HDAC1 (untagged)-Human histone deacetylase 1 (HDAC1), NM_004964.2, 10ug $185 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA501999 HDAC1 mouse monoclonal antibody, clone OTI2D2 (formerly 2D2), 100ul $325 In Stock
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OriGene Data
Vector:pCMV6-XL5 Insert Size: 2200 Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Stem cell relevant signaling - DSL/Notch pathwayStem cell - PluripotencyAdult stem cellsTranscription FactorsDruggable Genome
Protein Pathways: Cell cycleNotch signaling pathwayHuntington's diseasePathways in cancerChronic myeloid leukemia
Reference Data
RefSeq: NM_004964.2, NP_004955
RefSeq Size: 2091 RefSeq ORF: 1449
Synonyms : GON-10; HD1; RPD3; RPD3L1
LocusID: 3065 Cytogenetic: 1p34 Domains: Hist_deacetyl
Summary: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008].


* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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