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Home TrueClone CDH1 Clone

CDH1 (NM_004360) Human cDNA Clone

Specifications Citations (1) Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC117413 CDH1 (untagged)-Human cadherin 1, type 1, E-cadherin (epithelial) (CDH1) (10ug) NM_004360.2, 10ug $1590 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA800671 CDH1 (E Cadherin) mouse monoclonal antibody, Clone 1F3, 100ul $379 In Stock
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OriGene Data
Vector:pCMV6-XL4 Insert Size: 5000 Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: ES Cell Differentiation/IPSTransmembraneDruggable Genome
Protein Pathways: Cell adhesion molecules (CAMs)Adherens junctionPathogenic Escherichia coli infectionPathways in cancerEndometrial cancerThyroid cancerMore Pathways >>
Reference Data
RefSeq: NM_004360.2, NP_004351
RefSeq Size: 4815 RefSeq ORF: 2848
Synonyms : Arc-1; CD324; CDHE; ECAD; LCAM; UVO
LocusID: 999 Cytogenetic: 16q22.1 Domains: Cadherin_C_term, CA
Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008].


* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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