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Home TrueClone CHIT1 Clone

CHIT1 (NM_003465) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC117950 CHIT1 (untagged)-Human chitinase 1 (chitotriosidase) (CHIT1) (10ug) NM_003465.1, 10ug $680 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA309549 Goat Polyclonal Antibody against CHIT1 (aa409-423), 100ug $325 3-7 Days
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OriGene Data
Vector:pCMV6-XL4 Insert Size: 1750 Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Secreted ProteinTransmembrane
Protein Pathways: Amino sugar and nucleotide sugar metabolism
Reference Data
RefSeq: NM_003465.1, NP_003456
RefSeq Size: 1633 RefSeq ORF: 1401
Synonyms : CHI3; CHIT; CHITD
LocusID: 1118 Cytogenetic: 1q32.1 Domains: Glyco_hydro_18, CBM_14
Summary: Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2012].

Transcript Variant: This variant (1) is the predominant transcript and it encodes the longest isoform (1).

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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