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Home TrueClone PIK3CG Clone

PIK3CG (NM_002649) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC124070 PIK3CG (untagged)-Human phosphoinositide-3-kinase, catalytic, gamma polypeptide (PIK3CG) (10ug), NM_002649.2, 10ug $185 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA505228 PIK3CG mouse monoclonal antibody,clone 6H5, 100ul $325 In Stock
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OriGene Data
Vector:pCMV6-XL4 Insert Size: 4800 Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: ES Cell Differentiation/IPSDruggable Genome
Protein Pathways: Inositol phosphate metabolismErbB signaling pathwayChemokine signaling pathwayPhosphatidylinositol signaling systemmTOR signaling pathwayApoptosisMore Pathways >>
Reference Data
RefSeq: NM_002649.2, NP_002640
RefSeq Size: 5379 RefSeq ORF: 3309
Synonyms : p110gamma; p120-PI3K; PI3CG; PI3K; PI3Kgamma; PIK3
LocusID: 5294 Cytogenetic: 7q22.3
Summary: This gene encodes a protein that belongs to the pi3/pi4-kinase family of proteins. The gene product is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. The gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2013].

Transcript Variant: This variant (1) represents the longest transcript. All three variants encode the same protein.

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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