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Home TrueClone MAP3K11 Clone

MAP3K11 (NM_002419) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC110949 MAP3K11 (untagged)-Human mitogen-activated protein kinase kinase kinase 11 (MAP3K11) (10ug), NM_002419.3, 10ug $185 4 weeks
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA313098 Rabbit polyclonal anti-MLK3 antibody, 100ul $325 3 Weeks
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Click here for the corresponding kinase deficient mutant clone.
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Also for MAP3K11 (NM_002419)
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OriGene Data
Vector:pCMV6-XL5 Insert Size: 3860 Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Protein KinaseDruggable Genome
Protein Pathways: MAPK signaling pathway
Reference Data
RefSeq: NM_002419.3, NP_002410
RefSeq Size: 3574 RefSeq ORF: 2544
Synonyms : MEKK11; MLK-3; MLK3; PTK1; SPRK
LocusID: 4296 Cytogenetic: 11q13.1-q13.3 Domains: pkinase, TyrKc, SH3, S_TKc
Summary: The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase contains a SH3 domain and a leucine zipper-basic motif. This kinase preferentially activates MAPK8/JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF-kappaB mediated by Rho family GTPases and CDC42. [provided by RefSeq, Jul 2008].


* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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