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Home TrueClone GLB1 Clone

GLB1 (NM_001079811) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC315819 GLB1 (untagged)-Human galactosidase, beta 1 (GLB1), transcript variant 2 (10ug), NM_001079811.1, 10ug $680 3 weeks
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA505597 GLB1 mouse monoclonal antibody,clone 5H2, 100ul $325 In Stock
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OriGene Data
Vector:pCMV6 Entry Insert Size: Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Druggable Genome
Protein Pathways: Galactose metabolismOther glycan degradationGlycosaminoglycan degradationSphingolipid metabolismGlycosphingolipid biosynthesis - ganglio seriesMetabolic pathwaysMore Pathways >>
Reference Data
RefSeq: NM_001079811.1, NP_001073279
RefSeq Size: 2500 RefSeq ORF: 1944
Synonyms : EBP; ELNR1; MPS4B
LocusID: 2720 Cytogenetic: 3p21.33
Summary: This gene encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyzes the terminal beta-galactose from ganglioside substrates and other glycoconjugates. Defects in this gene are the cause of GM1-gangliosidosis and Morquio B syndrome. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008].

Transcript Variant: This variant (2) has an alternate 5' UTR and uses a downstream start codon, compared to variant 1. Isoform b has a shorter N-terminus, compared to isoform a.

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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