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Home TrueClone ANGPTL4 Clone

ANGPTL4 (NM_001039667) Human cDNA Clone

Specifications Citations (0) Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC310759 ANGPTL4 (untagged)-Human angiopoietin-like 4 (ANGPTL4), transcript variant 3, NM_001039667.1, 10ug $550 3 weeks
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA318914 Rabbit polyclonal anti-Angptl4 (FIAF) antibody, 100ug $325 3-7 Days
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OriGene Data
Vector:pCMV6 Entry QM Insert Size: Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Secreted ProteinDruggable Genome
Protein Pathways: PPAR signaling pathway
Reference Data
RefSeq: NM_001039667.1, NP_001034756
RefSeq Size: 1853 RefSeq ORF: 1107
Synonyms : ANGPTL2; ARP4; FIAF; HARP; HFARP; NL2; PGAR; pp1158; TGQTL; UNQ171
LocusID: 51129 Cytogenetic: 19p13.3
Summary: This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4. [provided by RefSeq, Sep 2013].

Transcript Variant: This variant (3) lacks an alternate in-frame exon compared to variant 1. The encoded isoform (b) is shorter than isoform a.

* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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