|
RefSeq: NM_001039468.1,
NP_001034557
LocusID:
2011
Cytogenetic:
11q12
Summary: EMK (ELKL Motif Kinase) is a small family of ser/thr protein kinases involved in the control of cell polarity, microtubule stability and cancer. Several cDNA clones have been isolated that encoded two isoforms of the human ser/thr protein kinase EMK1. These isoforms were characterized by the presence of a 162-bp alternative exon that gave rise to two forms, one containing the exon and the other one lacking it. Both forms were found to be coexpressed in a number of selected cell lines and tissue samples. The human EMK1 was shown to be encoded by a single mRNA ubiquitously expressed.
Transcript Variant: This variant (3) uses an alternate 5' exon and does not include two alternate coding exons. The resulting protein (isoform c) has a distinct N-terminus.
|
