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OriGene cDNAs in recent publications

BAT3 and SET1A form a complex with CTCFL/BORIS to modulate H3K4 histone dimethylation and gene expressionMol. Cell. Biol. Nov.2008; 28(21): p. 6720-6729 [BAT3]


Heme Oxygenase-1 Regulates Cardiac Mitochondrial Biogenesis via Nrf2-Mediated Transcriptional Control of Nuclear Respiratory Factor-1, Circ. Res., Oct 2008; 10.1161/01.RES.0000338597.71702.ad. [AKT1]


Interactions of S100A2 and S100A6 with the Tetratricopeptide Repeat Proteins, Hsp90/Hsp70-organizing Protein and Kinesin Light ChainJ. Biol. Chem., Oct 2008; 283: 28246 - 28258. [TOR1A]


Significance of Organic Cation Transporter 3 (SLC22A3) Expression for the Cytotoxic Effect of Oxaliplatin in Colorectal Cancer, Drug Metab. Dispos., Nov 2008; 36: 2299 - 2306. [POU5F1(OCT3)]


Stroma-dependent apoptosis in clonal hematopoietic precursors correlates with expression of PYCARD Blood, Oct 2008; 10.1182/blood-2008-04-152686. [TNFRSF1A] 

TRUECLONE COLLECTION

Cat. No. Ref. ID Description Delivery
SC302306 NM_001024847 Homo sapiens transforming growth factor, beta receptor II (70/80kDa) (TGFBR2), transcript variant 1 as transfection-ready DNA NM_001024847.1 4-5 weeks
Functional Details
Larger aliquots of this purified plasmid are available on the next page. For 50 ug and 100 ug orders, delivery will take four additional weeks from the estimated delivery time.


Potent 29-mer shRNA Available
Open Reading Frame Clones
Optimal Transfection Reagent
Antibody Search Option


Researchers who bought this clone have also purchased:
Western Blotting Reagents
MYC/DDK Tagged Western Blot Molecular Weight Markers
Anti-tag antibodies
HRP-Conjugated secondary antibodies and Western blot reagents
Insert Size determined experimentally by digestion of the clone with Not I restriction enzyme

Reference Data

Family: Kinase

RefSeq Size: 4714

RefSeq ORF: 1779

RefSeq: NM_001024847.1, NP_001020018
LocusID: 7048
Cytogenetic: 3p22
Summary: This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq].

Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (A).


family Pathway Function

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