OriGene cDNAs in recent publications

BAT3 and SET1A form a complex with CTCFL/BORIS to modulate H3K4 histone dimethylation and gene expression, Mol. Cell. Biol. Nov.2008; 28(21): p. 6720-6729 [BAT3]

Heme Oxygenase-1 Regulates Cardiac Mitochondrial Biogenesis via Nrf2-Mediated Transcriptional Control of Nuclear Respiratory Factor-1, Circ. Res., Oct 2008; 10.1161/01.RES.0000338597.71702.ad. [AKT1]

Interactions of S100A2 and S100A6 with the Tetratricopeptide Repeat Proteins, Hsp90/Hsp70-organizing Protein and Kinesin Light Chain, J. Biol. Chem., Oct 2008; 283: 28246 - 28258. [TOR1A]

Significance of Organic Cation Transporter 3 (SLC22A3) Expression for the Cytotoxic Effect of Oxaliplatin in Colorectal Cancer, Drug Metab. Dispos., Nov 2008; 36: 2299 - 2306. [POU5F1(OCT3)]

Stroma-dependent apoptosis in clonal hematopoietic precursors correlates with expression of PYCARD Blood, Oct 2008; 10.1182/blood-2008-04-152686. [TNFRSF1A]

TRUECLONE COLLECTION

Cat. No.	Ref. ID	Description	Delivery
SC300456	NM_001002838	Homo sapiens WNK lysine deficient protein kinase 3 (WNK3), transcript variant 2 as transfection-ready DNA NM_001002838.1	Please Inquire
		The use of this clone has been cited in the linked publication
Larger aliquots of this purified plasmid are available on the next page. For 50 ug and 100 ug orders, delivery will take four additional weeks from the estimated delivery time.

Researchers who bought this clone have also purchased:

RNA Interference Products

•

HuSH 29mer shRNA Constructs against WNK3

Related cDNA Clones from OriGene

•

Homo sapiens WNK lysine deficient protein kinase 3 (WNK3), transcript variant 1 as transfection-ready DNA

•

Homo sapiens WNK lysine deficient protein kinase 3 (WNK3), transcript variant 2 as transfection-ready DNA

Related ORF Clones from OriGene

•

ORF Clone of Homo sapiens WNK lysine deficient protein kinase 3 (WNK3), transcript variant 1 as transfection-ready DNA

•

ORF Clone of Homo sapiens WNK lysine deficient protein kinase 3 (WNK3), transcript variant 2 as transfection-ready DNA

Cloning Vectors

•	PrecisionShuttle - shuttle vectors for TrueORF
•	pCMV expression vector - for use as a negative control
•	pCMV NEOr vector - for stable cell line generation

Gene Expression Products

•	TissueScan Tissue qPCR Arrays
•	OriGene RapidScan Gene Expression Panels

Western Blotting Reagents

•	MYC/DDK Tagged Western Blot Molecular Weight Markers
•	Anti-tag antibodies
•	HRP-Conjugated secondary antibodies and Western blot reagents

Reference Data

Family: Kinase	RefSeq Size: 7572	RefSeq ORF: 5232
RefSeq: NM_001002838.1, NP_001002838 LocusID: 65267 Cytogenetic: Xp11.23 Summary: Members of the 'with no lysine' (WNK) kinase family, such as WNK3, are serine-threonine protein kinases that lack the almost invariant catalytic lysine in subdomain II, which is important for binding ATP in the catalytic site. Instead, these kinases have a conserved lysine in subdomain I that is thought to provide this function (Holden et al., 2004 [PubMed 15194194]).[supplied by OMIM]. Transcript Variant: This variant (2) lacks an in-frame segment and an in-frame exon in the coding region, as compared to variant 1. It encodes isoform 2 which lacks two internal segments, as compared to isoform 1.