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Over 1000 citations of OriGene cDNA clones
Silencing hsp25/hsp27 Gene Expression Augments Proteasome Activity and Increases CD8+ T-Cell–Mediated Tumor Killing and Memory Responses Cancer Prevention Research, Jan 2012; 5: 122 - 137. [HSPB1 ]

Activation of Androgen Receptor, Lipogenesis, and Oxidative Stress Converged by SREBP-1 Is Responsible for Regulating Growth and Progression of Prostate Cancer Cells Mol. Cancer Res., Jan 2012; 10: 133 - 142. [SREBF1 ]

Androgen Deprivation Causes Epithelial–Mesenchymal Transition in the Prostate: Implications for Androgen-Deprivation Therapy Cancer Res., Jan 2012; 72: 527 - 536. [AR ]

CB2 Cannabinoid Receptors Promote Neural Progenitor Cell Proliferation via mTORC1 Signaling J. Biol. Chem., Jan 2012; 287: 1198 - 1209. [Cnr2 ]

View All Citations >>

 

IGF1R (NM_000875) Human cDNA Clone

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Cat. No. Ref. ID Description Amount Price Shipping  
SC124152 NM_000875 Homo sapiens insulin-like growth factor 1 receptor (IGF1R) as transfection-ready DNA NM_000875.2 10ug $980 Next day Add to Shopping Cart
    
Click here to learn about OriGene’s recombinant IGF1R protein


OriGene TrueORF Data
Vector:pCMV6-XL4 Insert Size: 5500 Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Protein KinaseTransmembraneDruggable Genome
Protein Pathways: Oocyte meiosisEndocytosisFocal adhesionAdherens junctionLong-term depressionProgesterone-mediated oocyte maturationMore Pathways >>
Reference Data
RefSeq: NM_000875.2, NP_000866
RefSeq Size: 4989 RefSeq ORF: 4104
Synonyms : CD221; IGFIR; IGFR; JTK13; MGC142170; MGC142172; MGC18216
LocusID: 3480 Cytogenetic: 15q26.3
Summary: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. [provided by RefSeq].


Insert Size determined experimentally by digestion of the clone with Not I restriction enzyme

 

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