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Home TrueClone CYP2C18 Clone

CYP2C18 (NM_000772) Human cDNA Clone

Specifications Citations (1) Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC125486 CYP2C18 (untagged)-ORIGENE UNIQUE VARIANT 1 of Human cytochrome P450, family 2, subfamily C, polypeptide 18 (CYP2C18), (10ug), NM_000772.1, 10ug $680 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA313723 Rabbit polyclonal Cytochrome P450 2C8/9/18/19 antibody, 100ul $325 3 Weeks
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OriGene Data
Vector:pCMV6-XL4 Insert Size: 5000 Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence         
OTI Annotation: This TrueClone was found to represent an alternative form of the specific reference to which it is associated. Its Open Reading Frame (ORF) may represent a novel form or alternative splice variant. By virtue of it being a true transcript (cDNA clone not PCR product), it provides a biologically relevant copy of its mRNA template. For more details, please evaluate the sequence information provided on this website or contact our customer care specialists.
OTI Disclaimer: The sequence of an 'OriGene Unique Variant' differs significantly from the associated reference. It represents a novel splice variant from the same gene locus of the reference. Although such variants are true transcripts and present opportunity for discoveries, they are not yet curated by NCBI and should not be used if the exact reference accession sequence is required.
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: P450Druggable Genome
Protein Pathways: Arachidonic acid metabolismLinoleic acid metabolismRetinol metabolismMetabolism of xenobiotics by cytochrome P450Drug metabolism - cytochrome P450Metabolic pathways
Reference Data
RefSeq: NM_000772.1, NP_000763
RefSeq Size: 1995 RefSeq ORF: 1473
Synonyms : CPCI; CYP2C; CYP2C17; P450-6B/29C; P450IIC17
LocusID: 1562 Cytogenetic: 10q24 Domains: p450
Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum but its specific substrate has not yet been determined. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. An additional gene, CYP2C17, was once thought to exist; however, CYP2C17 is now considered an artefact based on a chimera of CYP2C18 and CYP2C19. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].


* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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