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Over 1000 citations of OriGene cDNA clones

Silencing hsp25/hsp27 Gene Expression Augments Proteasome Activity and Increases CD8+ T-Cell–Mediated Tumor Killing and Memory Responses Cancer Prevention Research, Jan 2012; 5: 122 - 137. [HSPB1 ]

Activation of Androgen Receptor, Lipogenesis, and Oxidative Stress Converged by SREBP-1 Is Responsible for Regulating Growth and Progression of Prostate Cancer Cells Mol. Cancer Res., Jan 2012; 10: 133 - 142. [SREBF1 ]

Androgen Deprivation Causes Epithelial–Mesenchymal Transition in the Prostate: Implications for Androgen-Deprivation Therapy Cancer Res., Jan 2012; 72: 527 - 536. [AR ]

CB2 Cannabinoid Receptors Promote Neural Progenitor Cell Proliferation via mTORC1 Signaling J. Biol. Chem., Jan 2012; 287: 1198 - 1209. [Cnr2 ]

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ADORA3 (NM_000677) Human cDNA Clone

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Cat. No.

Ref. ID

Description

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SC119759

NM_000677

Homo sapiens adenosine A3 receptor (ADORA3), transcript variant 2 as transfection-ready DNA NM_000677.2

10ug

$185

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Also for ADORA3 (NM_000677)

OriGene TrueORF Data

Vector:	pCMV6-XL4	Insert Size: 2300	Restriction Site:
Sequence Data:	Fully Sequenced ORF 5' Read Nucleotide Sequence
OTI Disclaimer:	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components:	The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families:	GPCR Transmembrane Druggable Genome
Protein Pathways:	Neuroactive ligand-receptor interaction

Reference Data

RefSeq: NM_000677.2, NP_000668	RefSeq Size: 2241	RefSeq ORF: 957
Synonyms : A3AR; AD026; bA552M11.5; RP11-552M11.7
LocusID: 140	Cytogenetic: 1p13.2
Summary: This gene encodes a protein that belongs to the family of adenosine receptors, which are G-protein-coupled receptors that are involved in a variety of intracellular signaling pathways and physiological functions. The receptor encoded by this gene mediates a sustained cardioprotective function during cardiac ischemia, it is involved in the inhibition of neutrophil degranulation in neutrophil-mediated tissue injury, it has been implicated in both neuroprotective and neurodegenerative effects, and it may also mediate both cell proliferation and cell death. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. Transcript Variant: This variant (2) lacks several exons in the 3' coding region, and contains an alternate exon, compared to variant 1. This results in a shorter isoform (2) with a distinct C-terminus, compared to isoform 1.