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Over 1000 citations of OriGene cDNA clones
Silencing hsp25/hsp27 Gene Expression Augments Proteasome Activity and Increases CD8+ T-Cell–Mediated Tumor Killing and Memory Responses Cancer Prevention Research, Jan 2012; 5: 122 - 137. [HSPB1 ]

Activation of Androgen Receptor, Lipogenesis, and Oxidative Stress Converged by SREBP-1 Is Responsible for Regulating Growth and Progression of Prostate Cancer Cells Mol. Cancer Res., Jan 2012; 10: 133 - 142. [SREBF1 ]

Androgen Deprivation Causes Epithelial–Mesenchymal Transition in the Prostate: Implications for Androgen-Deprivation Therapy Cancer Res., Jan 2012; 72: 527 - 536. [AR ]

CB2 Cannabinoid Receptors Promote Neural Progenitor Cell Proliferation via mTORC1 Signaling J. Biol. Chem., Jan 2012; 287: 1198 - 1209. [Cnr2 ]

View All Citations >>

 

KIT (NM_000222) Human cDNA Clone

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Cat. No. Ref. ID Description Amount Price Shipping  
SC120061 NM_000222 Homo sapiens v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog (KIT), transcript variant 1 as transfection-ready DNA NM_000222.1 10ug $185 Next day Add to Shopping Cart
Click here for the corresponding kinase deficient mutant clone.
    


OriGene TrueORF Data
Vector:pCMV6-XL5 Insert Size: 5450 Restriction Site: NotI-NotI
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: Protein KinaseES Cell Differentiation/IPSTransmembraneStem cell - PluripotencyAdult stem cellsEmbryonic stem cellsDruggable Genome
Protein Pathways: Cytokine-cytokine receptor interactionEndocytosisHematopoietic cell lineageMelanogenesisPathways in cancerAcute myeloid leukemia
Reference Data
RefSeq: NM_000222.1, NP_000213
RefSeq Size: 5084 RefSeq ORF: 2931
Synonyms : C-Kit; CD117; PBT; SCFR
LocusID: 3815 Cytogenetic: 4q11 Domains: pkinase, TyrKc, S_TKc, ig, IGc2, IG
Summary: This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).

Insert Size determined experimentally by digestion of the clone with Not I restriction enzyme

 

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