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HIV infection upregulates Caveolin 1 (Cav-1) expression to restrict virus production J. Virol., Jul 2010; 10.1128/JVI.00763-10. [CAV1]

JAK3 (NM_000215) Human cDNA Clone

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SC311134

NM_000215

Homo sapiens Janus kinase 3 (JAK3) as transfection-ready DNA NM_000215.2

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Also for JAK3 (NM_000215)

OriGene TrueClone Data

Vector:	pCMV6-XL5	Insert Size: 5500	Restriction Site:
Sequence Data:	Edited Nucleotide Sequence 5' Read Nucleotide Sequence 3' Read Nucleotide Sequence
OTI Annotation:	The open reading frame of this TrueClone was fully sequenced and found to be a perfect match to the protein associated to this reference.
OTI Disclaimer:	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components:	The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.

Reference Data

RefSeq: NM_000215.2, NP_000206	RefSeq Size: 4025	RefSeq ORF: 3375
Synonyms : JAK-3; JAK3_HUMAN; JAKL; L-JAK; LJAK
LocusID: 3718	Cytogenetic: 19p13.1	Domains: B41, pkinase, SH2, TyrKc, S_TKc
Summary: The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease). [provided by RefSeq].