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RefSeq: NM_000208.1,
NP_000199
LocusID:
3643
Cytogenetic:
19p13.3
Summary: After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (Long).
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