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Home TrueClone CYP17A1 Clone

CYP17A1 (NM_000102) Human cDNA Clone

Specifications Citations Clones of Other Species Product Documents
SKU Description Price Availibility*  
SC102224 CYP17A1 (untagged)-Human cytochrome P450, family 17, subfamily A, polypeptide 1 (CYP17A1) (10ug), NM_000102.2, 10ug $185 In Stock
TF81001 TurboFectin, High performance Transfection reagent (1ml/vial) $420 In Stock
TA503415 CYP17A1 mouse monoclonal antibody,clone 5G10, 100ul $325 In Stock
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Also for CYP17A1 (NM_000102)
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OriGene Data
Vector:pCMV6-XL4 Insert Size: 2500 Restriction Site:
Sequence Data: Fully Sequenced ORF          5' Read Nucleotide Sequence          3' Read Nucleotide Sequence         
OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Protein Families: P450Druggable Genome
Protein Pathways: C21-Steroid hormone metabolismMetabolic pathways
Reference Data
RefSeq: NM_000102.2, NP_000093
RefSeq Size: 1755 RefSeq ORF: 1527
Synonyms : CPT7; CYP17; P450C17; S17AH
LocusID: 1586 Cytogenetic: 10q24.3 Domains: p450
Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum. It has both 17alpha-hydroxylase and 17,20-lyase activities and is a key enzyme in the steroidogenic pathway that produces progestins, mineralocorticoids, glucocorticoids, androgens, and estrogens. Mutations in this gene are associated with isolated steroid-17 alpha-hydroxylase deficiency, 17-alpha-hydroxylase/17,20-lyase deficiency, pseudohermaphroditism, and adrenal hyperplasia. [provided by RefSeq, Jul 2008].


* Delivery time is an estimate in business days. Occasional delays may occur due to unforeseen complexities in the preparation of your construct. International customers may expect an additional 1-2 weeks in shipping

 

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