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RefSeq: NM_000061.1,
NP_000052
LocusID:
695
Cytogenetic:
Xq21.33
Domains: pkinase, SH2, TyrKc, SH3, BTK, PH, S_TKc
Summary: Defects in the Bruton tyrosine kinase (BTK) gene cause Agammaglobulinemia. Agammaglobulinemia is an X-linked immunodeficiency characterized by failure to produce mature B lymphocyte cells and associated with a failure of Ig heavy chain rearrangement. [provided by RefSeq].
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