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Genome Wide Full-Length cDNA Array
The post genomic area introduced many novel and exciting genome-wide assay platforms, including high-throughput gain-of-function screening, a rapidly emerging technique for identifying genes (see white paper and publications) that are involved in biological processes. OriGene introduced a growing number of GFC-Transfection Arrays as a revolutionary tools for this high-throughput functional screening method.
Our current GFC-Transfection Arrays cover a number of areas including:
Our coverage is always expanding based upon customer's input
GFC-Transfection Arrays are sets of CMV-driven expression ready individual cDNA clones arrayed in both 384 or 96 well formats (click on the corresponding Number of Genes in Array). Each clone is from OriGene’s TrueClone collection of full-length human cDNA clones and each clone is available separately for immediate shipment. GFC-Transfection Arrays are standardized, easy to use and ready for assay. With this product, researchers are no longer restricted to study one gene at a time, but can functionally screen thousands of genes (up to the entire genome) in fast, inexpensive and convenient gain-of-function assays.
The procedure is very simple, just add your reporter, transfection agent and cells, and score the array after 48 hours.
GFC-Transfection Arrays can be used to study a wide range of biological processes:
- Gene function
- Transcriptional regulation
- Association to specific pathway
- Cell and tissue-specific gene expression
- Cell proliferation and differentiation
- Developmental gene regulation
- Host-pathogen interactions
- Sensitivity to drugs and small molecules.
GFC-Transfection Arrays are adaptable for high-throughput readout assays that include:
- Reporter gene assays
- Receptor activation assays (e.g., G-protein coupled receptor assays)
- Nuclear translocations of protein markers
- Enzymatic assays
- Protein interaction assays
- Cell proliferation assays
- Apoptosis assays
- Cell toxicity assays
- Morphological assays