OriGene cDNAs in recent publications

Site-specific cleavage of GPCR-engaged Beta-arrestin: Influence of the AT1 receptor conformation on scissile site selection, J. Biol. Chem., Aug 2008; 283: 21612 - 21620 [ARRB2]

The lysosomal transmembrane protein 9B regulates the activity of inflammatory signaling pathways, J. Biol. Chem., Aug 2008; 283: 21487 - 21494 [RIPK1]

The lysosomal transmembrane protein 9B regulates the activity of inflammatory signaling pathways, J. Biol. Chem., Aug 2008; 283: 21487 - 21494 [TMEM9B]

A Novel Dysfunctional LHX4 Mutation with High Phenotypical Variability in Patients with Hypopituitarism, J. Clin. Endocrinol. Metab., Jul 2008; 93: 2790 - 2799 [LHX4]

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HEK 293T cells were plated at 10,000 cells/well in a 96-well plate in DMEM with 10% FBS. Both pCMV-luciferase and HuSH 29-mer shRNA-Luc were transfected using optimal ratios of DNA to each transfection reagent. Luciferase activity was measured at 48hrs. using BriteLite substrate (Perkin Elmer). Results are shown as percent silencing acheived for triplicate experiments.