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Over 1000 citations of OriGene cDNA clones
Epilepsy-associated GRIN2A mutations reduce NMDA receptor trafficking and agonist potency - molecular profiling and functional rescue Sci Rep 2017 [GRIN2A]

Aesculin modulates bone metabolism by suppressing receptor activator of NF-κB ligand (RANKL)-induced osteoclastogenesis and transduction signals Biochem. Biophys. Res. Commun. 2017 [TNFRSF11A]

A Naturally Occurring Isoform-Specific Probe for Highly Selective and Sensitive Detection of Human Cytochrome P450 3A5 J. Med. Chem. 2017 [CYP3A5]

Activation of Phenyl 4-(2-Oxo-3-alkylimidazolidin-1-yl)benzenesulfonates Prodrugs by CYP1A1 as New Antimitotics Targeting Breast Cancer Cells J. Med. Chem. 2017 [CYP1A1]

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TurboFectin 8.0 is optimal for shRNA delivery

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HEK 293T cells were plated at 10,000 cells/well in a 96-well plate in DMEM with 10% FBS. Both  pCMV-luciferase and HuSH 29-mer shRNA-Luc were transfected using optimal ratios of DNA to each transfection reagent. Luciferase activity was measured at 48hrs. using BriteLite substrate (Perkin Elmer). Results are shown as percent silencing acheived for triplicate experiments.

 

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