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Over 1000 citations of OriGene cDNA clones
1,2,4-Triazolyl octahydropyrrolo[2,3-b]pyrroles: A new series of potent and selective dopamine D3 receptor antagonists Bioorg. Med. Chem. Apr 2016 [DRD3]

A role for ABCG2 beyond drug transport: regulation of autophagy Autophagy Mar 2016 [ABCG2]

An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal NATURE COMMUNICATIONS Mar 2016 [U2AF2]

Aptamer-miRNA-212 Conjugate Sensitizes NSCLC Cells to TRAIL Molecular Therapy nucleic acid Mar 2016 [AXL]

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TurboFectin 8.0 is optimal for shRNA delivery

Double the knockdown efficiency!

hushlink

HEK 293T cells were plated at 10,000 cells/well in a 96-well plate in DMEM with 10% FBS. Both  pCMV-luciferase and HuSH 29-mer shRNA-Luc were transfected using optimal ratios of DNA to each transfection reagent. Luciferase activity was measured at 48hrs. using BriteLite substrate (Perkin Elmer). Results are shown as percent silencing acheived for triplicate experiments.

 

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