CLACP (COL25A1) Rabbit Polyclonal Antibody

CAT#: TA339614

Rabbit Polyclonal Anti-COL25A1 Antibody

Product Images

WB Suggested Anti-COL25A1 Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysate

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: The immunogen for anti-COL25A1 antibody: synthetic peptide directed towards the middle region of human COL25A1. Synthetic peptide located within the following region: GERGEAGPPGRGERGEPGAPGPKGKQGESGTRGPKGSKGDRGEKGDSGAQ
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
  Note that this product is shipped as lyophilized powder to China customers.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 64 kDa
• Gene Name: collagen type XXV alpha 1
• Database Link:
  NP_115907
  Entrez Gene 84570 Human
  UniProt ID Q9BXS0
• Background: COL25A1 is a brain-specific membrane-bound collagen. Proteolytic processing releases CLAC, a soluble form of COL25A1 containing the extracellular collagen domains that associates with senile plaques in Alzheimer disease (AD) brains. COL25A1 is a brain-specific membrane-bound collagen. Proteolytic processing releases CLAC, a soluble form of COL25A1 containing the extracellular collagen domains that associates with senile plaques in Alzheimer disease (AD; MIM 104300) brains (Osada et al., 2005 [PubMed 15615705]). [supplied by OMIM]
• Synonyms: AMY; CFEOM5; CLAC; CLAC-P; CLACP
• Note: Immunogen Sequence Homology: Dog: 100%; Human: 100%; Zebrafish: 100%; Rat: 93%; Horse: 93%; Mouse: 93%; Rabbit: 86%; Pig: 85%; Bovine: 85%; Guinea pig: 80%

Reference Data

• Protein Families: Transmembrane