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ALDH1A1 Rabbit Polyclonal Antibody
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USD 436.00
USD 200.00
USD 867.00
Specifications
| Product Data | |
| Applications | ICC/IF, IHC, WB |
| Recommended Dilution | WB 1:500 - 1:2000;IF 1:50- 1:200 |
| Reactivities | Human, Mouse, Rat |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Recombinant protein of human ALDH1A1 |
| Formulation | Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
| Concentration | lot specific |
| Purification | Affinity purification |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Gene Name | aldehyde dehydrogenase 1 family member A1 |
| Database Link | |
| Background | The aldehyde dehydrogenase family is a large group of enzymes that oxidize aldehydes formed through metabolic processes to their carboxylic acids. ALDH1A1 is a liver cytosolic isoform of acetaldehyde dehydrogenase and is involved in the major pathway of alcohol metabolism along with alcohol dehydrogenase. ALDH1A1 is also known as retinal dehydrogenase 1 and is involved in retinol metabolism, converting retinol to retinoic acid. Recent studies suggest that control of retinoid signaling through ALDH1A1 may influence hematopoietic stem cell differentiation. There has been recent interest in ALDH1 isoforms as predictive biomarkers in disease. Several studies have suggested that ALDH1A1 is a potential marker for cancer stem cells and chemoresistance in several tumor types, such as melanoma, lung cancer, glioblastoma. |
| Synonyms | ALDC; ALDH-E1; ALDH1; ALDH11; HEL-9; HEL-S-53e; HEL12; PUMB1; RALDH1 |
| Reference Data | |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS |
| Protein Pathways | Metabolic pathways, Retinol metabolism |
Documents
| Product Manuals |
| FAQs |
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