PPFIA3 Rabbit Polyclonal Antibody

CAT#: TA326678

Rabbit Polyclonal PPFIA3 Antibody

Product Images

Western blot analysis of PPFIA3 in 293 cell lysate with PPFIA3 antibody at (A) 1 and (B) 2 ug/ml.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1 - 2 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: PPFIA3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human PPFIA3
• Formulation: PPFIA3 antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1 mg/ml
• Purification: PPFIA3 antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: Predicted: 131 kDa; Observed: 131 kDa
• Gene Name: PTPRF interacting protein alpha 3
• Database Link:
  NP_003651
  Entrez Gene 76787 MouseEntrez Gene 140591 RatEntrez Gene 8541 Human
  UniProt ID O75145
• Background: The PPFIA3 protein is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family, a family of transmembrane protein tyrosine phosphatases known to be important for axon guidance and mammary gland development (1). Similar to the other liprin family members, PPFIA3 can interact with ERC2, a member of the ELKS-Rab6-interacting protein-CAST family of proteins at the presynaptic termini, suggesting that these proteins may play a role in the molecular organization of presynaptic zones (2).
• Synonyms: LPNA3

Reference Data

• Protein Families: Druggable Genome