CEBP Alpha (CEBPA) Rabbit Polyclonal Antibody
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Specifications
Product Data | |
Applications | WB |
Recommended Dilution | WB: 1:500-1:2000; IHC: 1:50-1:200 |
Reactivities | Human, Mouse, Rat |
Modifications | Phospho-specific |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | The antiserum was produced against A synthesized peptide derived from human C/EBP- alpha around the phosphorylation site of Serine 21 |
Formulation | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Concentration | lot specific |
Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide. |
Conjugation | Unconjugated |
Storage | Store at -20°C as received. |
Stability | Stable for 12 months from date of receipt. |
Predicted Protein Size | 45 kDa |
Gene Name | CCAAT/enhancer binding protein alpha |
Database Link | |
Background | The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. |
Synonyms | C; CEBP; EBP-alpha |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS |
Protein Pathways | Acute myeloid leukemia, Pathways in cancer |
Documents
Product Manuals |
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