COX5B Rabbit Polyclonal Antibody

CAT#: TA323101

Anti-COX5B Rabbit Polyclonal Antibody

Product Images

Predicted band size: 14 kDa. Positive control: Mouse heart and human liver cancer tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%+12%SDS-PAGE Lane 1: Mouse heart tissue lysate Lane 2: Human liver cancer tissue lysate Lysates: 40 ug per lane Primary antibody: 1/350 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 40 seconds)

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:1000-5000, WB: 1:200-1000
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Fusion protein corresponding to a region derived from 1-139 amino acids of human cytochrome c oxidase subunit Vb
• Formulation: PBS pH7.3, 0.05% NaN3, 50% glycerol
• Concentration: lot specific
• Purification: Antigen affinity purification
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 14 kDa
• Gene Name: cytochrome c oxidase subunit 5B
• Database Link:
  NP_001853
  Entrez Gene 12859 MouseEntrez Gene 94194 RatEntrez Gene 1329 Human
  UniProt ID P10606
• Background: Cytochrome C oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Vb of the human mitochondrial respiratory chain enzyme.
• Synonyms: COXVB

Reference Data

• Protein Pathways: Alzheimer's disease, Cardiac muscle contraction, Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease