TTYH1 Rabbit Polyclonal Antibody

CAT#: TA319973

Rabbit Polyclonal TTYH1 Antibody

Product Images

Western blot analysis of TTYH1 in Raji cell lysate with TTYH1 antibody at (A) 1 and (B) 2 ug/mL.

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  Immunocytochemistry of TTYH1 in Raji cells with TTYH1 antibody at 5 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 5 ug/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: TTYH1 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human TTYH1.
• Formulation: TTYH1 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: TTYH1 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: tweety family member 1
• Database Link:
  NP_001005367
  Entrez Gene 57348 Human
  UniProt ID Q9H313
• Background: TTYH1 Antibody: TTYH1 is a member of the tweety family of proteins, a family of chloride anion channels containing five transmembrane regions. TTYH1 is a Ca2+-independent, volume-sensitive large conductance chloride (Cl-) channel. TTYH1 is primarily expressed in neural tissue and upregulated in astrocytoma, glioma, and several other cancers. Recent experiments have shown that TTYH1 is an integral endoplasmic reticulum (ER) membrane protein involved in cell proliferation and is thought to play an essential role in embryonic cell growth, possibly through the Ca2+ storage/release process in ER membranes during early development.
• Synonyms: 4930459B04Rik; 6330408P11Rik; OTTMUSP00000024583; tty; tweety 1; tweety homolog 1 (Drosophila)