PRICKLE4 Rabbit Polyclonal Antibody

CAT#: TA319905

Rabbit Polyclonal PRICKLE4 Antibody

Product Images

Western blot analysis of PRICKLE4 in A549 cell lysate with PRICKLE4 antibody at 0.25 ug/ml in the (A) absence and (B) presence of blocking peptide.

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  Immunofluorescence of PRICKL4 in A549 cells with PRICKLE4 antibody at 20 ug/mL.

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  Immunocytochemistry of PRICKLE4 in A549 cells with PRICKLE4 antibody at 5 ug/mL.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: WB: 0.25 ug/mL, ICC: 5 ug/mL, IF: 5 ug/mL
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: PRICKLE4 antibody was raised against an 18 amino acid synthetic peptide near the amino terminus of human PRICKLE4.
• Formulation: PRICKLE4 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: PRICKLE4 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: prickle planar cell polarity protein 4
• Database Link:
  NP_037529
  Entrez Gene 29964 Human
  UniProt ID Q2TBC4
• Background: PRICKLE4 Antibody: PRICKLE4, also known as over-expressed breast tumor protein (OBTP), is a member of the LIM family of proteins. It possesses two LIM domains as well as a PET domain and is thought to localize to the nucleus. Its expression in multiple malignant tissue differentiations indicate that it may play a role in cancer differentiation. Two other members of the LIM family, PRICKLE1 and PRICKLE2, are thought to function in the noncanonical WNT signaling pathway which regulates intracellular calcium release and planar cell polarity, suggesting the PRICKLE4 may play a similar role.
• Synonyms: C6orf49; OBTP; OEBT; TOMM6