KPNA3 Rabbit Polyclonal Antibody

CAT#: TA319673

Rabbit Polyclonal KPNA3 Antibody

Product Images

Western blot analysis of KPNA3 in EL4 cell lysate with KPNA3 antibody at (A) 1 and (B) 2 ug/mL.

• 

  Immunocytochemistry of KPNA3 in HeLa cells with KPNA3 antibody at 10 ug/mL.

• 

  Immunofluorescence of KPNA3 in EL4 cells with KPNA3 antibody at 20 ug/mL.

• 

  Immunofluorescence of KPNA3 in EL4 cells with KPNA3 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 10 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: KPNA3 antibody was raised against a 14 amino acid synthetic peptide near the carboxy end of human KPNA3.
• Formulation: KPNA3 Antibody is supplied in PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: KPNA3 Antibody is affinity chromatography purified via peptide column.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: karyopherin subunit alpha 3
• Database Link:
  NP_002258
  Entrez Gene 16648 MouseEntrez Gene 361055 RatEntrez Gene 3839 Human
  UniProt ID O00505
• Background: KPNA3 Antibody: Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA3, the alpha subunit 3 of karyopherin, is silimar to human KPNA2, suggesting that KPNA3 may be involved in the nuclear transport system. It is ubiquitously expressed and recent studies have shown that human KPNA3 may be associated with schizophrenia.
• Synonyms: hSRP1; IPOA4; SRP1; SRP1gamma; SRP4