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XRCC3 Rabbit Polyclonal Antibody
CAT#: TA308545
Rabbit polyclonal antibody to XRCC3 (X-ray repair complementing defective repair in Chinese hamster cells 3)
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USD 200.00
USD 436.00
Specifications
| Product Data | |
| Applications | IF, WB |
| Recommended Dilution | ICC/IF:1:100-1:1000; WB:1:500-1:3000 |
| Reactivities | Human |
| Host | Rabbit |
| Isotype | IgG |
| Clonality | Polyclonal |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 202 and 346 of XRCC3 (Uniprot ID#O43542) |
| Formulation | 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative. |
| Concentration | lot specific |
| Purification | Purified by antigen-affinity chromatography. |
| Conjugation | Unconjugated |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 38 kDa |
| Gene Name | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| Database Link | |
| Background | This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq] |
| Synonyms | CMM6 |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Homologous recombination |
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