PNPT1 Rabbit Polyclonal Antibody

CAT#: TA308057

Rabbit Polyclonal antibody to PNPase (polyribonucleotide nucleotidyltransferase 1)

Product Images

Sample (50 ug of whole cell lysate). A: Mouse liver. 7.5% SDS PAGE. TA308057 diluted at 1:1000.

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  Sample (30 ug of whole cell lysate). A: JurKat. 7.5% SDS PAGE. TA308057 diluted at 1:1000.

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  Immunohistochemical analysis of paraffin-embedded Colon ca, using PNPase (TA308057) antibody at 1:250 dilution.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: IHC:1:100-1:1000; WB:1:500-1:3000
• Reactivities: Human, Mouse (Predicted: Rat, Cow)
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant fragment contain a sequence corresponding to a region within amino acids 25 and 251 of PNPase (Uniprot ID#Q8TCS8)
• Formulation: 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
• Concentration: lot specific
• Purification: Purified by antigen-affinity chromatography.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 86 kDa
• Gene Name: polyribonucleotide nucleotidyltransferase 1
• Database Link:
  NP_149100
  Entrez Gene 71701 MouseEntrez Gene 360992 RatEntrez Gene 87178 Human
  UniProt ID Q8TCS8
• Background: PNPT1 is a subunit of the exosome complex, which is involved in 3-prime-to-5-prime exoribonuclease activity for RNA processing and degradation (Raijmakers et al., 2002 [PubMed 12419256]). [supplied by OMIM]
• Synonyms: COXPD13; DFNB70; old-35; OLD35; PNPASE
• Note: Seq homology of immunogen across species: Rat (96%), Cow (94%)

Reference Data

• Protein Pathways: Purine metabolism, Pyrimidine metabolism, RNA degradation