TMEM70 Rabbit Polyclonal Antibody

CAT#: TA306941

Rabbit Polyclonal TMEM70 Antibody

Product Images

Western blot analysis of TMEM70 in human liver tissue lysate with TMEM70 antibody at 1 ug/mL.

• 

  Immunohistochemistry of TMEM70 in rat liver tissue with TMEM70 antibody at 5 ug/mL.

• 

  Immunofluorescence of TMEM70 in rat liver tissue with TMEM70 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: TMEM70 antibody was raised against a 14 amino acid peptide near the center of human TMEM70.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: transmembrane protein 70
• Database Link:
  NP_060336
  Entrez Gene 54968 Human
  UniProt ID Q9BUB7
• Background: TMEM70 is a recently identified mitochondrial protein that is thought to play a role in the biogenesis of the ATP synthase in higher eukaryotes. Mutations in this gene result in early neonatal onset of hypotonia, hypertrophic cardiomyopathy, lactic acidos and 3-methylglutaconic aciduria (3-MGC-uria), and usually cause death within the first six weeks of life, although some patients survive much longer. Little is known of the role of TMEM70, but it is conserved across multicellular eukaryotic organisms. It contains a conserved DUF1301 domain and two putative transmembrane regions.
• Synonyms: MC5DN2