SRPX2 Rabbit Polyclonal Antibody

CAT#: TA306870

Rabbit Polyclonal SRPX2 Antibody

Product Images

Western blot analysis of SRPX2 in human lung tissue lysate with SRPX2 antibody at (A) 1 and (B) 2 ug/ml.

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  Immunohistochemistry of SRPX2 in rat lung tissue with SRPX2 antibody at 5 ug/ml.

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  Immunofluorescence of SRPX2 in human lung tissue with SRPX2 antibody at 20 ug/mL.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: SRPX2 antibody was raised against a 16 amino acid peptide from near the amino terminus of human SRPX2.
• Formulation: PBS containing 0.02% sodium azide.
• Concentration: 1ug/ul
• Purification: Affinity chromatography purified via peptide column
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Gene Name: sushi repeat containing protein, X-linked 2
• Database Link:
  NP_055282
  Entrez Gene 68792 MouseEntrez Gene 317181 RatEntrez Gene 27286 Human
  UniProt ID O60687
• Background: Sushi-repeat-containing protein X-linked 2 (SRPX2) is a neural gene functioning in the speech and language center of the human brain; mutations in this gene lead to epilepsy, speech dyspraxia, mental retardation and cognitive disorders. Recently, SRPX2 was found to be a novel mediator of angiogenesis and can act as a ligand for the urokinase-type plasminogen activator, a protein that can facilitate invasive migration of sprouting endothelial cells. SRPX2 is also overexpressed in gastric cancer, leading to increased phosphorylation levels of focal adhesion kinase and enhanced cellular migration and adhesion, suggesting that SRPX2 may be a potential target in the treatment of metastatic cancers.
• Synonyms: BPP; CBPS; PMGX; RESDX; SRPUL

Reference Data

• Protein Families: Druggable Genome, Secreted Protein