BDKRB1 Goat Polyclonal Antibody

CAT#: TA302436

Goat Polyclonal Antibody against Bradykinin receptor B1

Product Images

TA302436 (2ug/ml) staining of K562 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

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  Figure from citation: Western Blot of BDKRB1 protein level by using anti-BDKRB1 antibody in HCMA segments. View Citation

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1:1,000. WB: 2-4µg/ml.
• Reactivities: Human
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Peptide with sequence KVWELYKQCTPK, from the internal region of the protein sequence according to NP_000701.2.
• Formulation: Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 44120 Da
• Gene Name: bradykinin receptor B1
• Database Link:
  NP_000701
  Entrez Gene 623 Human
  UniProt ID P46663
• Background: Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. [provided by RefSeq]
• Synonyms: B1BKR; B1R; BDKRB2; BKB1R; BKR1; BRADYB1

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Complement and coagulation cascades, Neuroactive ligand-receptor interaction, Regulation of actin cytoskeleton