PRMT8 Rabbit Polyclonal Antibody

CAT#: TA302105

Rabbit Polyclonal Antibody against PRMT8 (C-term)

Product Images

Western blot analysis of PRMT8 Antibody (C-term) (Cat.#TA302105) in K562 cell line lysates (35ug/lane). PRMT8 (arrow) was detected using the purified Pab.

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  Western blot analysis of PRMT8 (arrow) using rabbit polyclonal PRMT8 Antibody (C-term) (Cat.#TA302105). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PRMT8 gene (Lane 2) (Origene Technologies).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: WB: 1:1000
• Reactivities: Human (Predicted: Mouse)
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This PRMT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 344-373 amino acids from the C-terminal region of human PRMT8.
• Formulation: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
• Concentration: lot specific
• Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
• Conjugation: Unconjugated
• Storage: Store at -20°C as received.
• Stability: Stable for 12 months from date of receipt.
• Predicted Protein Size: 45160 Da
• Gene Name: protein arginine methyltransferase 8
• Database Link:
  NP_062828
  Entrez Gene 381813 MouseEntrez Gene 56341 Human
  UniProt ID Q9NR22
• Background: Protein arginine methylation plays a role in signal transduction, RNA processing, transcriptional regulation, and DNA repair. PRMT8, a protein arginine N-methyltransferase most closely related to PRMT1, methylates the guanidino nitrogens of arginyl residues in some proteins. This protein associates with the plasma membrane following myristoylation and exhibits a brain-specific expression pattern, making it unique within this family of enzymes.
• Synonyms: HRMT1L3; HRMT1L4

Reference Data

• Protein Families: Druggable Genome