Cardiac Troponin I (TNNI3) Mouse Monoclonal Antibody [Clone ID: 110 (10F4)]
CAT#: SM1371P
Cardiac Troponin I (TNNI3) mouse monoclonal antibody, clone 110 (10F4), Purified
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Specifications
Product Data | |
Clone Name | 110 (10F4) |
Applications | ELISA, WB |
Recommended Dilution | Suitable for ELISA and Western blotting. |
Reactivities | Bovine, Canine, Feline, Goat, Human, Porcine, Rabbit, Rat |
Host | Mouse |
Isotype | IgG2a |
Clonality | Monoclonal |
Immunogen | Purified human Cardiac Troponin I. |
Specificity | This antibody is specific for amino acids 34-37 of Troponin I from Human heart. There is no cross-reactivity with skeletal muscle Troponin I. |
Formulation | PBS pH 7.4, containing 0.09% Sodium Azide as preservative. State: Purified State: Liquid purified IgG fraction. |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein A. |
Conjugation | Unconjugated |
Storage | Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | troponin I3, cardiac type |
Database Link | |
Background | Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. E.g. TnI inhibits ATP-ase activity of acto-myosin. TnT and TnI are presented in cardiac muscles in different forms than in skeletal muscles. Only one tissue-specific isoform of TnI is described for cardiac muscle tissue (cTnI). cTnI is expressed only in myocardium |
Synonyms | TNNI3, TNNC1 |
Reference Data |
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