CKMB Mouse Monoclonal Antibody [Clone ID: 1F2/1]

CAT#: BM361

CKMB mouse monoclonal antibody, clone 1F2/1, Purified

Specifications

Product Data

• Clone Name: 1F2/1
• Applications: ELISA, R
• Recommended Dilution: ELISA.
  IRMA.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2b
• Clonality: Monoclonal
• Immunogen: Highly purified human CK-MB.
• Specificity: This antibody recognizes Creatine Phosphokinase MB isoforms MB1 and MB2. It shows less than 0.1% reactivity with CK-BB or CK-MM and minimal reactivity with other Human serum proteins.
• Formulation: PBS
  State: Purified
  State: Liquid purified IgG fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Background: Creatine Kinase MB consists of a dimer of nonidentical chains. With MM being the major form in skeletal muscle and myocardium, MB existing in myocardium, and BB existing in many tissues, especially brain.
  Creatine Kinase MB reversibly catalyses the transfer of phosphate between ATP and various phosphogens. The creatine kinase isoenzymes play a central role in energy transduction in tissues with large fluctuating energy demands such as skeletal muscle, heart, brain and spermatozoa.
  Creatine phosphokinase, also known as creatine kinase (CK), is an enzyme expressed by various tissues and cell types. CK catalyses the conversion of creatine and consumes adenosine triphosphate (ATP) to create phosphocreatine and adenosine diphosphate (ADP).
  In cells, the "cytosolic" CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are three different isoenzymes: CKMM, CKBB and CKMB.
  
  
• Synonyms: CK-MB, Creatine Kinase MB