Alkaline Phosphatase (ALPL) Mouse Monoclonal Antibody [Clone ID: BGN/03/661]

CAT#: BM216

Alkaline Phosphatase (ALPL) mouse monoclonal antibody, clone BGN/03/661, Purified

Specifications

Product Data

• Clone Name: BGN/03/661
• Applications: ELISA, WB
• Recommended Dilution: ELISA.
  Western blot: In Immunoblotting this antibody stains a band of BAP at around 70 kDa.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Alkaline Phosphatase prepared from Human bone.
• Specificity: The antibody clone BGN/03/661 is specific for Alkaline Phosphatase. It detects the tissue specific isotypes, BAP, PLAP, and IAP (Bone, Placental and Intestinal AP), but may react with other Alkaline Phosphatases.
• Formulation: PBS
  State: Purified
  State: Liquid purified IgG fraction
  Preservative: 0.09% Sodium Azide
• Concentration: lot specific
• Purification: Affinity Chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: alkaline phosphatase, liver/bone/kidney
• Database Link:
  Entrez Gene 249 Human
  UniProt ID P05186
• Background: Alkaline phosphatase (ALP) removes phosphate groups from the 5' end of DNA and RNA, and from proteins, at high pH. Most mammals have 4 different isozymes: placental, placental like, intestinal and non tissue specific (found in liver, kidney and bone). Tissues with particularly high concentrations of ALP include the liver, bile ducts, placenta, and bone. Damaged or diseased tissue releases enzymes into the blood, so serum ALP measurements can be abnormal in many conditions, including bone disease and liver disease.
• Synonyms: AP-TNAP, TNSALP