Dpysl2 Rabbit Polyclonal Antibody
Other products for "Dpysl2"
Specifications
Product Data | |
Applications | ELISA, IF, IHC, WB |
Recommended Dilution | ELISA. |
Reactivities | Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | A 15 residue synthetic peptide derived from C-terminal domain of Human Collapsing-Response Mediator. |
Specificity | This antibody reacts with 65 kDa CRMP-2. It do not react with CRMP-1, CRMP-3, CRMP-4 or CRMP-5. |
Formulation | State: Serum State: Lyophilized serum Preservative: None |
Reconstitution Method | Restore in distilled water. |
Conjugation | Unconjugated |
Storage | Store lyophilized at 2-8°C for 6 months or at -20°C long term. After reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C long term. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Gene Name | dihydropyrimidinase-like 2 |
Database Link | |
Background | CRMP2 is 62 kDa member of the dehydropyrimidinase family. It is involved in axon formation and outgrowth by transporting to axons, the actin cytoskeleton regulating; Rac1-associated protein 1 (Sra-1)/WASP family verprolin-homologous protein 1 (WAVE1) complex. CRMP2 also regulates axon formation and branching by binding tubulin heterodimers thereby enhancing microtubule polymerisation. Through its interaction with ROKalpha, CRMP2 is also thought to play a role in RhoA-dependent signalling. CRMP2 is associated with mesial temporal lobe epilepsy and schizophrenia. |
Synonyms | Dihydropyrimidinase-related protein 2, DRP-2, N2A3 |
Reference Data |
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