Troponin I fast skeletal muscle (TNNI2) (N-term) Rabbit Polyclonal Antibody

CAT#: AP54323PU-N

Troponin I fast skeletal muscle (TNNI2) (N-term) rabbit polyclonal antibody, Aff - Purified


USD 560.00

2 Weeks*

Size
    • 400 ul

Product Images

Other products for "Troponin I fast skeletal muscle"

Specifications

Product Data
Applications WB
Recommended Dilution ELISA: 1:1;000.
Western blot: 1:100~500.
Reactivities Human, Mouse
Host Rabbit
Isotype Ig
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human TNNI2
Specificity This antibody detects Fast skeletal muscle Troponin I (N-term).
Formulation PBS with 0.09% (W/V) sodium azide
State: Aff - Purified
State: Liquid Ig fraction
Concentration lot specific
Purification Protein A column followed by peptide affinity purification
Conjugation Unconjugated
Storage Store at 2 - 8 °C for up to six months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens troponin I2, fast skeletal type (TNNI2), transcript variant 2
Background This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq].
Synonyms TNNI2
Note Molecular Weight: 21339 Da
Reference Data

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.