PMS1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP53363PU-N

PMS1 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of PMS1 Antibody (C-term) in A549 cell line lysates (35ug/lane). This demonstrates the PMS1 antibody detected the PMS1 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100-1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 693-722 amino acids from the C-terminal region of human PMS1
• Specificity: This antibody recognizes Human PMS1 (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: PMS1 homolog 1, mismatch repair system component
• Database Link:
  Entrez Gene 5378 Human
  UniProt ID P54277
• Background: This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.
• Synonyms: PMSL1
• Note: Molecular Weight: 105830 Da

Reference Data

• Protein Families: Druggable Genome, Transcription Factors