NR2C1 (C-term) Rabbit Polyclonal Antibody

CAT#: AP52931PU-N

NR2C1 (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

NR2C1 Antibody (C-term) western blot analysis in HepG2 cell line lysates (3ug/lane).This demonstrates the NR2C1 antibody detected the NR2C1 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 515-545 amino acids from the C-terminal region of human NR2C1
• Specificity: This antibody reacts to NR2C1.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 67315 Da
• Gene Name: Homo sapiens nuclear receptor subfamily 2 group C member 1 (NR2C1), transcript variant 2
• Database Link:
  Entrez Gene 7181 Human
  UniProt ID P13056
• Background: This gene encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined.
• Synonyms: TR2

Reference Data

• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors