APPBP1 (NAE1) (Center) Rabbit Polyclonal Antibody
Other products for "APPBP1"
Specifications
Product Data | |
Applications | IHC, WB |
Recommended Dilution | ELISA: 1/1000. |
Reactivities | Human |
Host | Rabbit |
Isotype | Ig |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 171-200 amino acids from the Central region of human APPBP1 |
Specificity | This antibody recognizes Human APPBP1 (Center). |
Formulation | PBS containing 0.09% (W/V) Sodium Azide as preservative State: Aff - Purified State: Liquid purified Ig fraction |
Concentration | lot specific |
Purification | Protein A column, followed by peptide affinity purification |
Conjugation | Unconjugated |
Storage | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Stability | Shelf life: one year from despatch. |
Gene Name | Homo sapiens NEDD8 activating enzyme E1 subunit 1 (NAE1), transcript variant 2 |
Database Link | |
Background | The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene. |
Synonyms | NAE1, HPP1 |
Note | Molecular Weight: 60246 Da |
Reference Data | |
Protein Pathways | Alzheimer's disease |
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complexities in the preparation of your product. International customers may expect an additional 1-2 weeks
in shipping.