APPBP1 (NAE1) (Center) Rabbit Polyclonal Antibody

CAT#: AP52806PU-N

APPBP1 (NAE1) (Center) rabbit polyclonal antibody, Aff - Purified


USD 560.00

2 Weeks*

Size
    • 400 ul

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Specifications

Product Data
Applications IHC, WB
Recommended Dilution

ELISA: 1/1000.
Western Blot: 1/100-1/500. 
Immunohistochemistry on Paraffin Sections: 1/10-1/50.

Reactivities Human
Host Rabbit
Isotype Ig
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide between 171-200 amino acids from the Central region of human APPBP1
Specificity This antibody recognizes Human APPBP1 (Center).
Formulation PBS containing 0.09% (W/V) Sodium Azide as preservative
State: Aff - Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein A column, followed by peptide affinity purification
Conjugation Unconjugated
Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.

Stability Shelf life: one year from despatch.

Gene Name Homo sapiens NEDD8 activating enzyme E1 subunit 1 (NAE1), transcript variant 2
Background The protein encoded by this gene binds to the beta-amyloid precursor protein. Beta-amyloid precursor protein is a cell surface protein with signal-transducing properties, and it is thought to play a role in the pathogenesis of Alzheimer's disease. In addition, the encoded protein can form a heterodimer with UBE1C and bind and activate NEDD8, a ubiquitin-like protein. This protein is required for cell cycle progression through the S/M checkpoint. Three transcript variants encoding different isoforms have been found for this gene.
Synonyms NAE1, HPP1
Note Molecular Weight: 60246 Da
Reference Data
Protein Pathways Alzheimer's disease

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.