BTBD14A (NACC2) (C-term) Rabbit Polyclonal Antibody

CAT#: AP52805PU-N

BTBD14A (NACC2) (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of NACC2 / BTBD14A Antibody (C-term) in A2058 cell line lysates (35ug/lane).

Specifications

Product Data

• Applications: WB
• Recommended Dilution:

  ELISA: 1/1000.
  Western Blot: 1/100-1/500.

• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 472-502 amino acids from the C-terminal region of human NACC2 / BTBD14A
• Specificity: This antibody recognizes Human NACC2 / BTBD14A (C-term).
• Formulation: PBS containing 0.09% (W/V) Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification
• Conjugation: Unconjugated
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Gene Name: NACC family member 2
• Database Link:
  Entrez Gene 138151 Human
  UniProt ID Q96BF6
• Background: BTBD14A (BTB/POZ domain-containing protein 14A), also known as BTBD14, is a 587 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD14A may play a role in transcription regulation.
• Synonyms: BEND9; BTBD14; BTBD14A; MGC23427; OTTHUMP00000022564
• Note: Molecular Weight: 62837 Da